Quantitative EEG Publications

Journal Articles

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What Is Quantitative EEG?

David A. Kaiser PhD (2008)

Abstract

Basic description of quantitative electroencephalography (EEG) in the context of neurotherapeutic application. Issues associated with spectral analysis of human EEG are discussed and an example quantitative EEG assessment report is provided. The human brain is the most resilient and adaptable structure in nature, the source of all of our emotions, perceptions, thoughts, and behaviors. The brain is made up of hundreds of billions of microscopic elements called neurons which use chemical messages to regulate electrical activity throughout the brain. The brain communicates to itself and with the body by means of these electrical changes and our emotions, perceptions, thoughts, and behaviors are the result of the totality of these electrical and chemical changes, although the exact mechanism of how brain becomes mind is not understood. The purpose of this paper is to provide a description of the brain¡¯s electrical activity, how it can be measured and how a quantitative EEG (QEEG) report can be used to guide neurofeedback treatment.


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Quantitative EEG Publications and Scientific Articles:

Real-time quantitative monitoring of cerebral blood flow by laser speckle contrast imaging after cardiac arrest with targeted temperature management.
He J, Lu H, Young L, Deng R, Callow D, Tong S, Jia X.
J Cereb Blood Flow Metab. 2017 Jan 1:271678X17748787. doi: 10.1177/0271678X17748787. [Epub ahead of print]

Change in Quantitative EEG Theta Cordance as a Potential Predictor of Repetitive Transcranial Magnetic Stimulation Clinical Outcome in Major Depressive Disorder.
Hunter AM, Nghiem TX, Cook IA, Krantz DE, Minzenberg MJ, Leuchter AF.
Clin EEG Neurosci. 2017 Nov 1:1550059417746212. doi: 10.1177/1550059417746212. [Epub ahead of print]

Pharmacology in translation; the preclinical and early clinical profile of the novel ¥á2/3 functionally selective GABAA receptor positive allosteric modulator PF-06372865.
Nickolls SA, Gurrell R, van Amerongen G, Kammonen J, Cao L, Brown AR, Stead C, Mead A, Watson C, Hsu C, Owen RM, Pike A, Fish RL, Chen L, Qiu R, Morris ED, Feng G, Whitlock M, Gorman D, van Gerven J, Reynolds DS, Dua P, Butt RP.
Br J Pharmacol. 2017 Dec 7. doi: 10.1111/bph.14119. [Epub ahead of print]

Traumatic brain injury: An EEG point of view.
Ianof JN, Anghinah R.
Dement Neuropsychol. 2017 Jan-Mar;11(1):3-5. doi: 10.1590/1980-57642016dn11-010002. Review.

Effect of sedation on quantitative electroencephalography after cardiac arrest.
Drohan CM, Cardi AI, Rittenberger JC, Popescu A, Callaway CW, Baldwin ME, Elmer J.
Resuscitation. 2017 Dec 2. pii: S0300-9572(17)30759-1. doi: 10.1016/j.resuscitation.2017.11.068. [Epub ahead of print]

Cardiovascular Disease Risk Factors in Patients with Posttraumatic Stress Disorder (PTSD): A Narrative Review.
Šagud M, Jakšić N, Vuksan-Ćusa B, Lončar M, Lončar I, Peleš AM, Miličić D, Jakovljević M.
Psychiatr Danub. 2017 Dec;29(4):421-430. doi: 10.24869/psyd.2017.421.

Quantitative EEG Parameters for Prediction of Outcome in Severe Traumatic Brain Injury: Development Study.
Tolonen A, Särkelä MOK, Takala RSK, Katila A, Frantzén J, Posti JP, Müller M, van Gils M, Tenovuo O.
Clin EEG Neurosci. 2017 Nov 1:1550059417742232. doi: 10.1177/1550059417742232. [Epub ahead of print]

Effects of Transcranial Direct Current Stimulation, Transcranial Pulsed Current Stimulation, and Their Combination on Brain Oscillations in Patients with Chronic Visceral Pain: A Pilot Crossover Randomized Controlled Study.
Thibaut A, Russo C, Hurtado-Puerto AM, Morales-Quezada JL, Deitos A, Petrozza JC, Freedman S, Fregni F.
Front Neurol. 2017 Nov 1;8:576. doi: 10.3389/fneur.2017.00576. eCollection 2017.

Train of four stimulation artifact mimicking a seizure during computerized automated ICU EEG monitoring.
Dhakal LP, Tatum WO, Freeman WD.
Epilepsy Behav Case Rep. 2017 Sep 11;8:69-72. doi: 10.1016/j.ebcr.2017.09.002. eCollection 2017.

Prediction of cognitive worsening in de novo Parkinson's disease: Clinical use of biomarkers.
Arnaldi D, De Carli F, Famà F, Brugnolo A, Girtler N, Picco A, Pardini M, Accardo J, Proietti L, Massa F, Bauckneht M, Morbelli S, Sambuceti G, Nobili F.
Mov Disord. 2017 Dec;32(12):1738-1747. doi: 10.1002/mds.27190. Epub 2017 Nov 9.

QEEG-based neural correlates of decision making in a well-trained eight year-old chess player.
Alipour A, Seifzadeh S, Aligholi H, Nami M.
J Integr Neurosci. 2017 Oct 25. doi: 10.3233/JIN-170056. [Epub ahead of print]

Iron therapy substantially restores qEEG maturational lag among iron-deficient anemic infants.
Otero GA, Fernández T, Pliego-Rivero FB, Mendieta GG.
Nutr Neurosci. 2017 Oct 24:1-10. doi: 10.1080/1028415X.2017.1391529. [Epub ahead of print]

Index of Theta/Alpha Ratio of the Quantitative Electroencephalogram in Alzheimer's Disease: A Case-Control Study.
Fahimi G, Tabatabaei SM, Fahimi E, Rajebi H.
Acta Med Iran. 2017 Aug;55(8):502-506.

Response to Pharmacological Treatment in Major Depression Predicted by Electroencephalographic Alpha Power - a Pilot Naturalistic Study.
Kandilarova SS, Terziyski KV, Draganova AI, Stoyanov DS, Akabaliev VH, Kostianev SS.
Folia Med (Plovdiv). 2017 Sep 1;59(3):318-325. doi: 10.1515/folmed-2017-0040.

A Preliminary Study on qEEG in Burn Patients With Chronic Pruritus.
Miraval FK, Shie VL, Morales-Quezada L, Santiago C, Fernandes-Marcondes B, Nadler D, Ryan CM, Schneider JC, Fregni F.
Ann Rehabil Med. 2017 Aug;41(4):693-700. doi: 10.5535/arm.2017.41.4.693. Epub 2017 Aug 31.

Acute single channel EEG predictors of cognitive function after stroke.
Aminov A, Rogers JM, Johnstone SJ, Middleton S, Wilson PH.
PLoS One. 2017 Oct 2;12(10):e0185841. doi: 10.1371/journal.pone.0185841. eCollection 2017.

How high level of anxiety in Panic Disorder can interfere in working memory? A computer simulation and electrophysiological investigation.
Di Giorgio Silva LW, Aprigio D, Di Giacomo J, Gongora M, Budde H, Bittencourt J, Cagy M, Teixeira S, Ribeiro P, de Carvalho MR, Freire R, Nardi AE, Basile LF, Velasques B.
J Psychiatr Res. 2017 Dec;95:238-246. doi: 10.1016/j.jpsychires.2017.08.021. Epub 2017 Sep 11.

Evaluation of auditory perception development in neonates by quantitative electroencephalography and auditory event-related potentials.
Zhang Q, Cheng Q, Li H, Dong X, Tu W.
PLoS One. 2017 Sep 14;12(9):e0183728. doi: 10.1371/journal.pone.0183728. eCollection 2017.

Apathy in Patients with Parkinson's Disease Correlates with Alteration of Left Fronto-Polar Electroencephalographic Connectivity.
Hatz F, Meyer A, Zimmermann R, Gschwandtner U, Fuhr P.
Front Aging Neurosci. 2017 Aug 15;9:262. doi: 10.3389/fnagi.2017.00262. eCollection 2017.

Electroencephalogram Abnormalities During Positional Changes in Brain Sagging Syndrome.
Bensam B, Sy HL, Sotudeh N, Bhalla PK, Hwang ST, LeDoux DE.
J Clin Neurophysiol. 2017 Aug 30. doi: 10.1097/WNP.0000000000000409. [Epub ahead of print]

Average spectral power changes at the hippocampal electroencephalogram in schizophrenia model induced by ketamine.
Sampaio LRL, Borges LTN, Silva JMF, de Andrade FRO, Barbosa TM, Oliveira TQ, Macedo D, Lima RF, Dantas LP, Patrocinio MCA, do Vale OC, Vasconcelos SMM.
Fundam Clin Pharmacol. 2017 Aug 29. doi: 10.1111/fcp.12319. [Epub ahead of print]

Neuropsychiatric characteristics of antiterrorist operation combatants in the Donbass (Ukraine).
Loganovsky KN, Zdanevich NA, Gresko MV, Marazziti D, Loganovskaja TK.
CNS Spectr. 2017 Aug 15:1-7. doi: 10.1017/S1092852917000190. [Epub ahead of print]

Delta Power Is Higher and More Symmetrical in Ischemic Stroke Patients with Cortical Involvement.
Fanciullacci C, Bertolucci F, Lamola G, Panarese A, Artoni F, Micera S, Rossi B, Chisari C.
Front Hum Neurosci. 2017 Jul 28;11:385. doi: 10.3389/fnhum.2017.00385. eCollection 2017.

Effect of essential oil and supercritical carbon dioxide extract from the root of Angelica gigas on human EEG activity.
Sowndhararajan K, Seo M, Kim M, Kim H, Kim S.
Complement Ther Clin Pract. 2017 Aug;28:161-168. doi: 10.1016/j.ctcp.2017.05.010. Epub 2017 May 26.

Longitudinal Dynamics of 3-Dimensional Components of Selfhood After Severe Traumatic Brain Injury: A qEEG Case Study.
Fingelkurts AA, Fingelkurts AA.
Clin EEG Neurosci. 2017 Sep;48(5):327-337. doi: 10.1177/1550059417696180. Epub 2017 Feb 1.

Quantitative EEG findings and response to treatment with antiepileptic medications in children with epilepsy.
Ouyang CS, Chiang CT, Yang RC, Wu RC, Wu HC, Lin LC.
Brain Dev. 2018 Jan;40(1):26-35. doi: 10.1016/j.braindev.2017.07.004. Epub 2017 Jul 28.

Evaluation of a novel median power spectrogram for seizure detection by non-neurophysiologists.
Yan P, Melman T, Yan S, Otgonsuren M, Grinspan Z.
Seizure. 2017 Aug;50:109-117. doi: 10.1016/j.seizure.2017.06.016. Epub 2017 Jun 15.

qEEG by neurointensivists: research agenda and implications for training.
Biasucci DG, Caricato A, Citerio G.
Intensive Care Med. 2017 Nov;43(11):1747-1748. doi: 10.1007/s00134-017-4887-9. Epub 2017 Jul 19. No abstract available.

Assessing quantitative EEG spectrograms to identify non-epileptic events.
Goenka A, Boro A, Yozawitz E.
Epileptic Disord. 2017 Sep 1;19(3):299-306. doi: 10.1684/epd.2017.0921.

Evaluating cognitive complaints in breast cancer survivors with the FACT-Cog and quantitative electroencephalography.
Van Dyk K, Hunter AM, Ercoli L, Petersen L, Leuchter AF, Ganz PA.
Breast Cancer Res Treat. 2017 Nov;166(1):157-166. doi: 10.1007/s10549-017-4390-6. Epub 2017 Jul 13.

Brain Responses to a 6-Hz Binaural Beat: Effects on General Theta Rhythm and Frontal Midline Theta Activity.
Jirakittayakorn N, Wongsawat Y.
Front Neurosci. 2017 Jun 28;11:365. doi: 10.3389/fnins.2017.00365. eCollection 2017.

Quantitative EEG Metrics Differ Between Outcome Groups and Change Over the First 72 h in Comatose Cardiac Arrest Patients.
Wiley SL, Razavi B, Krishnamohan P, Mlynash M, Eyngorn I, Meador KJ, Hirsch KG.
Neurocrit Care. 2017 Jun 23. doi: 10.1007/s12028-017-0419-2. [Epub ahead of print]

A Brain Electrical Activity Electroencephalographic-Based Biomarker of Functional Impairment in Traumatic Brain Injury: A Multi-Site Validation Trial.
Hanley D, Prichep LS, Badjatia N, Bazarian J, Chiacchierini R, Curley KC, Garrett J, Jones E, Naunheim R, O'Neil B, O'Neill J, Wright DW, Huff JS.
J Neurotrauma. 2018 Jan 1;35(1):41-47. doi: 10.1089/neu.2017.5004. Epub 2017 Sep 21.

Comparison of Electroencephalography (EEG) Coherence between Major Depressive Disorder (MDD) without Comorbidity and MDD Comorbid with Internet Gaming Disorder.
Youh J, Hong JS, Han DH, Chung US, Min KJ, Lee YS, Kim SM.
J Korean Med Sci. 2017 Jul;32(7):1160-1165. doi: 10.3346/jkms.2017.32.7.1160.

Altered EEG spectral power during rest and cognitive performance: a comparison of preterm-born adolescents to adolescents with ADHD.
Rommel AS, James SN, McLoughlin G, Brandeis D, Banaschewski T, Asherson P, Kuntsi J.
Eur Child Adolesc Psychiatry. 2017 Dec;26(12):1511-1522. doi: 10.1007/s00787-017-1010-2. Epub 2017 Jun 2.

A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus.
Song JJ, Kim K, Sunwoo W, Mertens G, Van de Heyning P, De Ridder D, Vanneste S, Lee SY, Park KJ, Choi H, Choi JW.
Front Hum Neurosci. 2017 May 18;11:210. doi: 10.3389/fnhum.2017.00210. eCollection 2017.

Quantitative EEG evaluation for performance level analysis of professional female soccer players.
Tharawadeepimuk K, Wongsawat Y.
Cogn Neurodyn. 2017 Jun;11(3):233-244. doi: 10.1007/s11571-017-9427-3. Epub 2017 Feb 24.

Correlates of sleep quality in midlife and beyond: a machine learning analysis.
Kaplan KA, Hardas PP, Redline S, Zeitzer JM; Sleep Heart Health Study Research Group.
Sleep Med. 2017 Jun;34:162-167. doi: 10.1016/j.sleep.2017.03.004. Epub 2017 Mar 27.

Advances in functional brain imaging technology and developmental neuro-psychology: their applications in the Jungian analytic domain.
Petchkovsky L.
J Anal Psychol. 2017 Jun;62(3):415-433. doi: 10.1111/1468-5922.12320.

The state of everyday quantitative EEG use in Canada: A national technologist survey.
Ng MC, Gillis K.
Seizure. 2017 Jul;49:5-7. doi: 10.1016/j.seizure.2017.05.003. Epub 2017 May 5.

Portable qEEG and HD-tCS Device for Point-of-Injury Traumatic Brain Injury Diagnostics.
Strisland F, Vedum J, Liverud A, Dalgard S, Br©ªdreskift T, Albert B, Noyvirt A, Setchi R, Vene K, Herranen H, Kirs M, Antal A, Schellhorn K, Sjaaheim H.
Stud Health Technol Inform. 2017;237:198-203.

Differences in Resting-state Quantitative Electroencephalography Patterns in Attention Deficit/Hyperactivity Disorder with or without Comorbid Symptoms.
Kim JW, Kim SY, Choi JW, Kim KM, Nam SH, Min KJ, Lee YS, Choi TY.
Clin Psychopharmacol Neurosci. 2017 May 31;15(2):138-145. doi: 10.9758/cpn.2017.15.2.138.

Predicting success of vagus nerve stimulation (VNS) from EEG symmetry.
Hilderink J, Tjepkema-Cloostermans MC, Geertsema A, Glastra-Zwiers J, de Vos CC.
Seizure. 2017 May;48:69-73. doi: 10.1016/j.seizure.2017.03.020. Epub 2017 Apr 4.

Quantitative Electroencephalographic Biomarkers in Preclinical and Human Studies of Huntington's Disease: Are They Fit-for-Purpose for Treatment Development?
Leuchter MK, Donzis EJ, Cepeda C, Hunter AM, Estrada-Sánchez AM, Cook IA, Levine MS, Leuchter AF.
Front Neurol. 2017 Mar 30;8:91. doi: 10.3389/fneur.2017.00091. eCollection 2017. Review.

Quantitative electroencephalograms and neuro-optometry: a case study that explores changes in electrophysiology while wearing therapeutic eyeglasses.
Zelinsky D, Feinberg C.
Neurophotonics. 2017 Jan;4(1):011013. doi: 10.1117/1.NPh.4.1.011013. Epub 2017 Mar 15.

Quantitative electroencephalogram measures in adult obstructive sleep apnea - Potential biomarkers of neurobehavioural functioning.
D'Rozario AL, Cross NE, Vakulin A, Bartlett DJ, Wong KKH, Wang D, Grunstein RR.
Sleep Med Rev. 2017 Dec;36:29-42. doi: 10.1016/j.smrv.2016.10.003. Epub 2016 Oct 19. Review.

Implementation of continuous qEEG in two neurointensive care units by intensivists: a feasibility study.
Citerio G, Patruno A, Beretta S, Longhi L, Frigeni B, Lorini L; Continuous Quantified EEG in NeuroIntensive Care (CrazyEEG) Group.
Intensive Care Med. 2017 Jul;43(7):1067-1068. doi: 10.1007/s00134-017-4775-3. Epub 2017 Apr 4. No abstract available.

Quantitative EEG for Predicting Upper Limb Motor Recovery in Chronic Stroke Robot-Assisted Rehabilitation.
Trujillo P, Mastropietro A, Scano A, Chiavenna A, Mrakic-Sposta S, Caimmi M, Molteni F, Rizzo G.
IEEE Trans Neural Syst Rehabil Eng. 2017 Jul;25(7):1058-1067. doi: 10.1109/TNSRE.2017.2678161. Epub 2017 Mar 3.

Predicting rapid cognitive decline in Alzheimer's disease patients using quantitative EEG markers and neuropsychological test scores.
Reyes-Coronel C, Waser M, Garn H, Deistler M, Dal-Bianco P, Benke T, Ransmayr G, Grossegger D, Schmidt R.
Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:6078-6081. doi: 10.1109/EMBC.2016.7592115.

Increased prognostic accuracy of TBI when a brain electrical activity biomarker is added to loss of consciousness (LOC).
Hack D, Huff JS, Curley K, Naunheim R, Ghosh Dastidar S, Prichep LS.
Am J Emerg Med. 2017 Jul;35(7):949-952. doi: 10.1016/j.ajem.2017.01.060. Epub 2017 Feb 20.

Three-dimensional components of selfhood in treatment-naive patients with major depressive disorder: A resting-state qEEG imaging study.
Fingelkurts AA, Fingelkurts AA.
Neuropsychologia. 2017 May;99:30-36. doi: 10.1016/j.neuropsychologia.2017.02.020. Epub 2017 Feb 28.

Differential diagnosis between patients with probable Alzheimer's disease, Parkinson's disease dementia, or dementia with Lewy bodies and frontotemporal dementia, behavioral variant, using quantitative electroencephalographic features.
Garn H, Coronel C, Waser M, Caravias G, Ransmayr G.
J Neural Transm (Vienna). 2017 May;124(5):569-581. doi: 10.1007/s00702-017-1699-6. Epub 2017 Feb 27.

Effects of observation of hand movements reflected in a mirror on cortical activation in patients with stroke.
Chang MY, Kim HH, Kim KM, Oh JS, Jang C, Yoon TH.
J Phys Ther Sci. 2017 Jan;29(1):38-42. doi: 10.1589/jpts.29.38. Epub 2017 Jan 30.

Electroencephalographic Correlates of Suicidal Ideation in the Theta Band.
Lee SM, Jang KI, Chae JH.
Clin EEG Neurosci. 2017 Sep;48(5):316-321. doi: 10.1177/1550059417692083. Epub 2017 Feb 15.

In patients suffering from major depressive disorders, quantitative EEG showed favorable changes in left and right prefrontal cortex.
Haghighi M, Ludyga S, Rahimi B, Jahangard L, Ahmadpanah M, Torabian S, Esnaashari F, Nazaribadie M, Bajoghli H, Sadeghi Bahmani D, Holsboer-Trachsler E, Brand S.
Psychiatry Res. 2017 May;251:137-141. doi: 10.1016/j.psychres.2017.02.012. Epub 2017 Feb 6.

Quantitative EEG (QEEG) Measures Differentiate Parkinson's Disease (PD) Patients from Healthy Controls (HC).
Chaturvedi M, Hatz F, Gschwandtner U, Bogaarts JG, Meyer A, Fuhr P, Roth V.
Front Aging Neurosci. 2017 Jan 23;9:3. doi: 10.3389/fnagi.2017.00003. eCollection 2017.

Comparison of QEEG Findings between Adolescents with Attention Deficit Hyperactivity Disorder (ADHD) without Comorbidity and ADHD Comorbid with Internet Gaming Disorder.
Park JH, Hong JS, Han DH, Min KJ, Lee YS, Kee BS, Kim SM.
J Korean Med Sci. 2017 Mar;32(3):514-521. doi: 10.3346/jkms.2017.32.3.514.

Poststroke QEEG informs early prognostication of cognitive impairment.
Schleiger E, Wong A, Read S, Rowland T, Finnigan S.
Psychophysiology. 2017 Feb;54(2):301-309. doi: 10.1111/psyp.12785. Epub 2016 Nov 7.

Neurophysiological assessment of brain dysfunction in critically ill patients: an update.
Azabou E, Fischer C, Guerit JM, Annane D, Mauguiere F, Lofaso F, Sharshar T.
Neurol Sci. 2017 May;38(5):715-726. doi: 10.1007/s10072-017-2824-x. Epub 2017 Jan 21. Review.

Quantitative EEG in obstructive sleep apnea syndrome: a review of the literature.
Puskás S, Kozák N, Sulina D, Csiba L, Magyar MT.
Rev Neurosci. 2017 Apr 1;28(3):265-270. doi: 10.1515/revneuro-2016-0064. Review.